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fentanyl, cyproheptadine. Possibly will increase toxicity of your other by pharmacodynamic synergism. Modify Therapy/Keep an eye on Closely. Coadministration of fentanyl with anticholinergics could raise risk for urinary retention and/or serious constipation, which may bring on paralytic ileus.If coadministration of CYP3A4 inhibitors with fentanyl